Sodium Phenyl Butyrate (SPB) (CAS No.: 1716-12-7)

Sodium Phenyl Butyrate (SPB) (CAS No.: 1716-12-7) Specification

Storage
Other

Ph Level
6.5 TO 8

Smell
Sharp

Medicine Name
NA

Chemical Name
Sodium 4-phenylbutanoate

CAS No
1716-12-7

Type
Other

Grade
Medicine Grade

Usage
Pharmaceutical Sector: Utilized as a core active ingredient in formulations designed to manage urea cycle disorders (UCDs) by providing an alternative pathway for waste nitrogen excretion.

Purity(%)
98%

Physical Form
Powder

Sodium Phenyl Butyrate (SPB) (CAS No.: 1716-12-7) Trade Information

Minimum Order Quantity
100 Kilograms

FOB Port
HAZIRA,BHAVNAGAR

Payment Terms
Paypal, Cheque, Letter of Credit at Sight (Sight L/C), Telegraphic Transfer (T/T), Western Union, Letter of Credit (L/C)

Supply Ability
5000 Kilograms Per Month

Delivery Time
10 Days

Sample Available
No

Sample Policy
Contact us for information regarding our sample policy

Packaging Details
AS PER BUYER REQUIREMENT

Main Export Market(s)
Asia, Australia, South America, Central America

Main Domestic Market
All India

Certifications
CERTIFIED

About Sodium Phenyl Butyrate (SPB) (CAS No.: 1716-12-7)

Sodium Phenyl Butyrate

Product Description

Sodium Phenyl Butyrate is a well-known chemical compound primarily utilized as an active pharmaceutical ingredient (API) and a specialized laboratory reagent. It serves as a structural analogue to butyrate, functioning efficiently as an ammonia scavenger and a histone deacetylase (HDAC) inhibitor. The compound appears as a white to off-white crystalline powder that exhibits high solubility in aqueous solutions.

Technical Specifications

Chemical Name: Sodium 4-phenylbutanoate
Molecular Formula: C10H11NaO2
Molecular Weight: 186.18 g/mol
CAS Number: 1716-12-7
Assay (Purity): 98.0% to 102.0% on a dried basis
Appearance: White to off-white crystalline powder
Solubility: Freely soluble in water and methanol
Melting Point: 198 to 202 degrees Celsius
Loss on Drying: Maximum 0.5%
Heavy Metals: Maximum 20 ppm
pH Range: 6.5 to 8.0 (in 10% aqueous solution)

Industrial Applications

Pharmaceutical Sector: Utilized as a core active ingredient in formulations designed to manage urea cycle disorders (UCDs) by providing an alternative pathway for waste nitrogen excretion.
Biochemical Research: Employed extensively in laboratory settings to study cell differentiation, apoptosis, and gene expression alteration through HDAC inhibition.
Chemical Synthesis: Acts as an intermediate and precursor for organic synthesis and the development of specialized chemical derivatives.

Packaging and Storage Information

Standard Packaging: Available in 25 kg fiber drums with double polythene inner liners, or in customized smaller packaging sizes to meet specific industrial requirements.
Storage Conditions: Store in tightly sealed containers in a cool, dry, and well-ventilated warehouse facility. Keep away from direct sunlight, moisture, heat sources, and incompatible oxidizing agents.

High Purity Medicine Grade for Specialized Applications

Our Sodium Phenyl Butyrate is offered in a purity of 98% and meets medicine grade standards, ensuring suitability for critical pharmaceutical applications. It serves as a reliable component in the formulation of drugs that address metabolic conditions, particularly urea cycle disorders. Sourced and manufactured with stringent quality controls, our product helps maintain efficacy and safety in pharmaceutical preparations.

Pharmaceutical Utility in Urea Cycle Disorder Management

Sodium Phenyl Butyrate plays a pivotal role in treating urea cycle disorders by offering patients an alternative route for waste nitrogen elimination. This mechanism supports the body's ability to manage excess ammonia, which is essential in individuals with compromised urea cycles. As a result, SPB is a preferred choice in pharmaceutical research and product development for metabolic disorder therapies.

FAQ's of Sodium Phenyl Butyrate (SPB) (CAS No.: 1716-12-7):

Q: How is Sodium Phenyl Butyrate used in pharmaceutical formulations?

A: Sodium Phenyl Butyrate is incorporated as an active ingredient in medications designed to manage urea cycle disorders. It facilitates the excretion of waste nitrogen, helping the body eliminate excess ammonia in patients where the natural urea cycle is defective.

Q: What is the benefit of using Sodium Phenyl Butyrate for urea cycle disorders?

A: The main benefit is its ability to provide an alternative pathway for waste nitrogen removal, which helps prevent the dangerous accumulation of ammonia in the bloodstream and supports better metabolic stability.

Q: When should Sodium Phenyl Butyrate be administered in clinical settings?

A: SPB is typically prescribed when patients are diagnosed with urea cycle disorders and require medical intervention to control ammonia levels. Dosage and administration are determined by a healthcare professional based on individual patient needs.

Q: Where is your Sodium Phenyl Butyrate manufactured and supplied from?

A: Our Sodium Phenyl Butyrate is manufactured and exported from India, adhering to international quality standards to ensure reliable supply for pharmaceutical manufacturers worldwide.

Q: What is the typical physical form and pH of Sodium Phenyl Butyrate supplied?

A: It is provided as a fine powder with a pH range of 6.5 to 8, and it has a sharp smell. This form allows easy handling and integration into various formulations.

Q: Can you explain the process behind Sodium Phenyl Butyrate's function in metabolic management?

A: Sodium Phenyl Butyrate works by offering a chemical pathway that binds with nitrogen-containing compounds. This bond allows excess waste nitrogen to be excreted via the kidneys, bypassing the malfunctioning urea cycle.